This document serves as a comprehensive guide for land managers considering mastication as a vegetation management tool. It synthesizes current scientific knowledge, detailing the characteristics and costs of various mastication equipment, including carrier machines and cutting heads. The report also summarizes the ecological effects of mastication on vegetation, soils, and wildlife habitat, noting the variability of these impacts across different ecosystems. It provides decision trees and implementation criteria to aid managers in selecting the most appropriate treatment methods and mastication configurations based on their specific site conditions and management objectives.